Alexx is a medical examiner, originally from Queens, New York but currently employed by the Miami-Dade Police. She is married with two children and is always upbeat and has a good bedside manner with her patients, despite being a coroner. Alexx has a tendency, displayed in many episodes, to talk to the corpses she is examining. She often addresses the corpses as "sweetie", "honey", or "baby" in a maternal way. She has a close relationship with Horatio Caine and his team of CSIs from the lab. This has led to friction in the autopsy room from her fellow MEs as well as her boss, who at one point tells her to transfer to night shift if she wishes to have any future promotions.

She has had to autopsy several people she knew, including CSI Tim Speedle (episode 301, "Lost Son") and Officer Aaron Jessop (episode 425, "One of Our Own").

Alexx is very maternal by nature and looks out for her co-workers as though they were her children. This is evident in season 4 of the show when she continues to care for and worry about Ryan Wolfe after he is injured by a nail gun. She prescribes him antibiotics after he experiences vision troubles (episode 410, "Shattered"). She is the first person he sounds out as the possible mole in the lab and is hurt by his suspicion. In the episode Nothing To Lose from season three, Alexx is held hostage by a serial killer.

She is superficially injured when a rocket is launched at the courthouse where she is preparing to give testimony. Alexx immediately begins to treat the wounded while the police attempt to discover the reason for the attack (episode 514, "No Man's Land"). When Eric Delko is shot in the head not long afterwards, she and her colleagues at the crime lab express great concern over his well-being. Alexx is the first to point out that because of the nature of the injury, Delko, if he should recover, might not be the same person they knew before (episode 515, "Man Down").

She is also seen addressing her own children in a very natural maternal way when talking about "bad people" to them after a case involving a child.

She often comments that the victims were too young to die. It is nearly her mantra.